The candidate should have a degree in Medicine & Surgery, Medical Biotechnology, Molecular Biotechnology, Neuroscience, Biology or Biomedical EngineeringHe/she should have an experience in a biomedical laboratory, including molecular biology and histology, possibly of the nervous system.
The research team works at the Neuroscience Institute Cavalieri Ottolenghi of Torino (https://www.Nico.Ottolenghi.Unito.It/eng) of which AV is scientific director. The main goal of NICO research center is to study the fundamental biological mechanisms of nervous system function, whose knowledge is essential for the development of innovative therapeutic approaches for neurodegenerative diseases and psychiatric disorders. The team is large (https://www.Nico.Ottolenghi.Unito.It/eng/Research/Research-Groups/Brain-development-and-disease), and is involved in two University spinoffs. The team, belonging to the Department of Neuroscience of UNITO, has many collaborations with clinicians. We study the development of the central nervous system from the embryo to the aged, and the common neurobiological mechanisms and molecular pathways which lead to normal development and to neurodegeneration. We believe that basic and applied neuroscience are strongly interconnected. Since many neurobiological molecular mechanisms can be studied at different levels, we use cell cultures and in vivo models, from simple organisms to rodents.We are interested in the molecular pathways leading to neurogenesis and neuronal cell death, which we study in development and in experimental models of transient/permanent cerebral ischemia, acute/chronic glaucoma, epilepsy and Alzheimer’s disease. Finally, we are studying the immunomodulatory, neuroprotective and growth promoting roles of cell therapy in SMA, ALS and spinal cord injury, particularly related to neuroinflammation.